Síntesis y caracterización de vidrio bioactivo 45S5 libre de alcóxidos obtenido por química suave

Abstract

Biomaterials for application in bone regeneration are ceramic, metallic, and alloys. Ceramic biomaterials are the most biocompatible with the body; however, they do not have adequate mechanical properties. In addition, synthesis methods require complex technology and large amounts of energy and time, so alternative methods are being investigated. In this research, a bioglass 45S5 of the system (SiO₂-CaO-Na₂O-P₂O₅) was developed by the sol-gel process from the substitution of alkoxides by a salt. In addition, heat treatment with a conventional microwave oven was assisted. The developed bioglass in this research presented the estimated elemental ratios and amorphous structure. The evaluation of the bioactivity of the bioglasses was confirmed in vitro by immersion in simulated physiological fluid for periods of 7, 14 and 21 days and the presence of phosphate groups on the surface of the material was corroborated.